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CORvalenM™
is an all natural dietary supplement designed to rebuild energy at the
cellular level. ribose ribose,ribose,d-ribose
What is ribose?
D-ribose is a simple, 5-carbon monosaccharide, or pentose sugar. It is used by all the cells of the body and is an essential compound in energy metabolism. Ribose is also the carbohydrate backbone of genetic material, DNA and RNA, certain vitamins and other important cellular compounds.
Who needs supplemental ribose?
Everyone needs ribose. It is an essential ingredient in stimulating natural energy production. Research has shown that ribose promotes cardiovascular health, reduces cardiac stress associated with strenuous activity and helps athletes reach new heights. Ribose helps hearts and muscles maximize energy recovery. Whether you are a trained athlete, a weekend warrior or are concerned about your cardiovascular health, ribose may help give the energy boost your body needs.
How is ribose made in the body?
All the necessary compounds for life are made in the body through a series of complicated biochemical metabolic pathways. Ribose is no different. In the body, ribose is made from glucose (a simple 6-carbon sugar) through a pathway called the Pentose Phosphate Pathway (PPP) or Hexose Monophosphate Shunt (HMS). Unfortunately, in heart and muscle cells important enzymes that regulate the activity of this pathway are lacking. As such, forming ribose in heart and muscle cells is a slow process. As a result heart and muscle tissues are unable to replace energy pools quickly once they have been depleted by disease or exercise.
How does the body derive cellular energy from ribose?
The physiologically functional form of ribose, called 5-phosphoribosyl-1-pyrophosphate (PRPP), regulates the metabolic pathway that synthesizes energy compounds in all living tissue. If this compound is not available in sufficient quantity, energy synthesis slows.
How does taking supplemental ribose aid in increasing cellular energy?
If the cellular energy pool is depleted by disease or exercise it must be replaced. PRPP is required to turn on the metabolic pathway used by the body to replenish these energy pools. Supplemental ribose bypasses the slow and rate limiting Pentose Phosphate Pathway, forms PRPP, and quickly begins the process of energy synthesis.
What will ribose do for someone concerned about cardiovascular health?
Numerous medical studies have shown that energy levels in the heart can be dramatically lowered by exercise or decreased blood flow associated with certain cardiac diseases. Depleted cardiac energy pools may be associated with increased cardiac stress, reduced blood flow to the periphery of the body, fatigue and decreased exercise tolerance. Ribose is the key nutrient for quickly restoring cardiac energy stores.
What is the recommended daily dosage of ribose?
For energy enhancement, � to 1 teaspoon (about 2 - 5 grams) is generally adequate. Bioenergy RIBOSE is mildly sweet and completely soluble. It mixes easily with your favorite juice, milk or other cold foods.
To maximize athletic performance, or to keep energy pools high during strenuous activity, slightly larger doses may be required. Bioenergy RIBOSE should be taken just before and just after exercise or activity. For extended exercise, an additional 1 - 2 grams per hour of exercise or activity may be helpful.
Are there any side effects associated with taking ribose?
Ribose should be taken in doses up to 5 grams (approximately 1 rounded teaspoon) at a time. Multiple 5-gram doses separated by 30 - 45 minutes can be taken without side effects. There are two known side effects of taking ribose in doses of 10 grams or more on an empty stomach. The first is a transient hypoglycemia (low blood sugar) that can be eliminated by taking larger doses of ribose with other carbohydrates (such as in juice). The second side effect that may occur in some individuals is loose stools. Again, this side effect has only been reported in very large doses, greater than 10 grams. Total daily intake of ribose should be limited to 20 grams, or approximately 4 rounded teaspoonfuls.
What will ribose do for someone who exercises on a regular basis?
Scientific research shows that three or four workouts per week may not allow enough rest time between sessions for heart and muscle energy pools to return to normal levels. Taking Bioenergy RIBOSE shortens the time needed by heart and muscle tissue to replace energy that is lost through vigorous exercise. Keeping energy pools full helps to keep hearts and muscles in good physiological condition, increase power and endurance, and reduce fatigue. Recent research has also shown that ribose supplementation during exercise reduces free radical formation and lowers cardiac stress associated with hypoxia.
Does ribose work with creatine or other supplements?
Ribose can increase the effect of creatine and other energy supplements by keeping the energy pool at full capacity. Creatine works by recycling energy that is already present in the tissue. Another supplement, carnitine, aids in fatty acid metabolism. A third, pyruvate, also helps to recycle energy. None of these other supplements, however, help to maintain the pool of energy in the cell. Only ribose performs this important metabolic function. Without adequate levels of energy to work with, no other supplement can be fully effective.
Why is the use of ribose on the rise?
Traditionally, ribose has been very expensive to produce making it difficult to offer as a nutritional supplement. New technology has brought production costs down.
In addition, ribose is safe and proven effective by many clinical and laboratory studies. Over 70 scientific publications describe the beneficial effects of ribose in hearts and muscles.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Intellectual Property
Research Library
The Sinatra Solution is an important read for anyone who cares about heart health. If you are a health professional, Dr. Sinatra will give you the science you need to make good, informed choices for your patients. If you simply want help keeping your heart healthy, you'll learn what you need to know. But if you or someone you love has heart disease, The Sinatra Solution is especially significant.
Millions of Americans suffer from debilitating
fatigue, myalgia (muscle pain), soreness, stiffness and shortness of
breath, impacting every aspect of life. For these people, going
to work can often be a challenge. They struggle to participate in
family activities and there's certainly no energy left for leisure or
hobbies. Friends have even learned not to depend on them.
And, since they often don't look sick, lack of understanding can make
the situation worse.
These symptoms can come from many sources. A variety of
conditions can leave people constantly fatigued, out of breath, stiff
and sore, making it impossible to face life's daily activities.
The overexertion of exercise can weaken muscles and drain energy
reserves, leaving people tired and out of sorts for days. Often,
this fatigue, shortness of breath, soreness, stiffness, and general
lack of well being are associated with depleted energy from the cells
and tissues.
CORvalenM can help. The active ingredients in CORvalenM
are clinically proven to be essential in the process of rebuilding
cellular energy. And more energy in your cells means less
fatigue, more overall energy, reduced muscle soreness and stiffness -
all contributing to a greater feeling of well being and improved
quality of life.
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